Kenneth "Supreme" McGriff, 50 Cent & Murder Inc.
Supreme and his nephew Gerald "Prince" Miller were the leaders of the Supreme Team, a Queens-based gang that sold truckloads of cocaine throughout the '80s and parts of the '90s.
When Irv Gotti, Ja Rule and their Murder Inc. crew were coming up in the rap game, Supreme was one of the people the rappers hung out with and shouted out in various songs.
Their association led to a federal investigation in 2003, claiming that Irv started his label using some of Preme’s drug money. The FEDs didn’t have enough evidence and Irv and his label were eventually found not guilty in court.
In 2007, Preme was convicted of murder-for-hire, on charges that he paid $50,000 to have rapper/drug dealer Eric "E-Money Bags" Smith and "Big Nose" Troy Singleton killed.
Preme seemed to play a part in the beef between 50 Cent and Murder Inc. 50 and Preme have some kind of past together, with 50 even shouting the crew out in his 1999 song "Ghetto Qur’an (Forgive Me)": Yo, when you hear talk of the Southside, you hear talk of the team. See, ni*gas feared Prince and respected Preme. For all you slow muthaf*ckas Ima break it down iller, see Preme was a business man and Prince was the killer."