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Giuliana Rancic is closing out on what was undeniably the hardest year of her life, but the E! News host remains optimistic and thankful.

VIDEO: Oh No! Giuliana Rancic Will Undergo Another Surgery For Breast Cancer

After being diagnosed with breast cancer and undergoing a double mastectomy after radiation treatments failed to combat the Cancer, Giuliana has remained enthusiastically optimistic.

Giuliana took to twitter yesterday to thank her greatest supporter, her husband Bill Rancic.

In an earlier interview, the E! News presenter told US Weekly Bill has been assuring her every step of the way, and has told her he doesn’t care what her breasts look like following the surgery. 

PHOTOS x VIDEO: Giuliana Rancic Reveals She Has Breast Cancer 

‘He looked at me and said, ‘I want you to know that I could not care less about the physical aspect of this. I need you here to be my wife, and I need you here to be the mother of my children one day.’

Very Sweet! We wish Giuliana a speedy recovery through this tough time and many happy and healthy years ahead.