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Since the death of Amy Winehouse, a slew of celebrities have taken to Twitter to express how heartbroken they are by the tragedy.

Some of Amy’s best friends have reacted in different ways over how her death has hurt them down to the core.

Russell Brand paid tribute on his website as he explained how addiction leaves everyone expecting that scary phone call.

Russell Brand’s Heartfelt Tribute To Amy Winehouse (PHOTOS)

But Amy’s BFF Kelly Osbourne is more than completely devastated. Kelly was spotted looking extremely distressed while she arrived in London upon hearing the news of the death of her best friend.

Take a look through some pictures of Kelly Osbourne and Amy together over the years.

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Amy and her goddaughter with Kelly.

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Kelly and Amy at an event.

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Kelly and Amy hang out at a music festival.

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Kelly and Amy at an Elle event in London.

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Paris Hilton with Kelly and Amy.

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Happier times with Kelly and Amy with Perez Hilton.

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Kelly tweeted, “I can’t even breath right now im crying so hard i just lost 1 of my best friends. i love you forever Amy & i will never forget the real you!”